All-natural ingredients like citrus juices, zest, lemongrass, juniper berries, and all-spice berries are blended to maintain the original Langdon's Original Tonic recipe, which is sweetened with Sucralose, a low-calorie artificial sweetener. Quinine is sourced naturally from the bark of the Cinchona tree, allowing for each 16-ounce bottle to produce up to 32 cocktails.